Citation Information :
Aghade SM. Prevalence of Metabolic Syndrome among Reproductiveaged Women with Polycystic Ovarian Syndrome: A Study from West-Central India. Indian J Med Biochem 2018; 22 (1):61-65.
Introduction: Polycystic ovarian syndrome (PCOS) is the most common hormonal disorder prevailing in premenopausal women. These patients are 11 times more likely to encounter metabolic syndrome (MetS). There is a substantial overlap into the components of these two syndromes, which in turn leads to increased risk of type-2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD) in the foreseeable future. In this perspective, the present study was planned to evaluate the prevalence of MetS and its individual components in PCOS in Indian scenario.
Study design: This cross-sectional study included 150 women diagnosed with PCOS between 18 and 38 years age. Demographic variables including age, education, occupation, inhabitant area, history of infertility, and family history of diabetes mellitus and hypertension were collected. Anthropometric parameters like weight, height, body mass index (BMI), waist circumference (WC), and systolic/diastolic blood pressure (SBP/ DBP) were measured. Fasting venous blood samples were collected and analyzed for biochemical parameters like glucose, total cholesterol (TC), triglycerides (TG), and high-density lipoprotein (HDL) cholesterol.
Result: The prevalence of MetS in women with PCOS was 38.67%. The most prevalent component was decreased HDL (84.67%), followed by increased WC (75.33%), followed by raised TG (42%).
Conclusion: The analogy of PCOS with MetS implicates that it is crucial to analyze the emerging trend of MetS in patients with PCOS. Recognition of this high-risk group will aid in the enforcement of preventive strategies including therapeutic lifestyle modifications and risk factor management. This will have a promising impact on women's health and will prevent or delay the outset of varying cardiometabolic complications in PCOS.
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