Indian Journal of Medical Biochemistry

Register      Login

VOLUME 22 , ISSUE 2 ( July-December, 2018 ) > List of Articles


Serum Sodium and Potassium Levels in Preeclampsia: A Clinical Study

Mrinal Gupta, Navanil Roy

Keywords : Antenatal care, Hypertension, Preeclampsia

Citation Information : Gupta M, Roy N. Serum Sodium and Potassium Levels in Preeclampsia: A Clinical Study. Indian J Med Biochem 2018; 22 (2):105-107.

DOI: 10.5005/jp-journals-10054-0065

License: CC BY-NC 3.0

Published Online: 01-12-2018

Copyright Statement:  Copyright © 2018; The Author(s).


Introduction: Preeclampsia is a disorder marked by the onset of hypertension and a significant amount of protein in the urine which begins after 20 weeks of pregnancy. Aim and objectives: To evaluate the role of serum sodium and potassium levels as a predisposing factor in the etiology of preeclampsia in pregnant women living in Bhilai, Chhattisgarh. Material and methods: It was a retrospective cross-sectional study, conducted in the Department of Biochemistry at Shri Shankracharya Institute of Medical Science and Hospital, Bhilai, Chhattisgarh a tertiary care institute. Results: The mean serum sodium level in preeclamptics was 123.9 ± 3.03 mmol/L and in normotensives was 140.6 ± 1.73 mmol/L which was statistically significant (p-value < 0.05). The mean serum potassium levels in preeclamptics were 2.49 ± 0.23 mmol/L and in normotensives was 3.96 ± 0.32 mmol/L which was statistically significant (p-value <0.05). Conclusion: Serum sodium level was observed to be reduced in preeclampsia compared to normotensive pregnant women. Early diagnosis and counseling of preeclampsia should be done at regular intervals for such cases to prevent any antenatal complications.

PDF Share
  1. Sukonpan K, Phupong V. Serum calcium and serum magnesium in normal and preeclamptic pregnancy. Archives of Gynecology and Obstetrics 2005 Nov;273:12-16.
  2. Ziaei, S., Ranjkesh, F., & Faghihzadeh, S. Evaluation of 24-hour urine copper in preeclamptic vs. normotensive pregnant and non-pregnant women. IJFS, 2008 May-Jun;2 (1):9-12.
  3. Park K. (ed.) Preventative medicine in obstetrics, pediatrics and geriatrics. In Park's textbook of preventive and social medicine, 21st edn. M/s BanarasidasBhanot publishers 2011:514-17.
  4. Sonagra AD, Dattatreya K, Murthy JDS. Serum LDH, ALP and uric acid in hypertensive disorders of pregnancy. IJPBS 2012;2(3):201-209.
  5. Sunitha T, Sameera K, Umaramani G. Study of Biochemical changes in Preeclamptic women. International Journal of Biological & Medical Research. 2012 Aug;3(3):2025- 2028.
  6. Davey DA, MacGillivray I. The classification & definition of the hypertensive disorders of pregnancy. Am J Obstet Gynecol. 1988 Apr;158(4):892-898.
  7. Clark SL, Cotton DB, Hankins G, Phelan JP. (Eds.). Critical care obstetrics (3rd ed.).1991; Oklahoma, OK: Black Well Science Limited. 95.
  8. Adewolu O. Serum sodium, potassium, calcium and magnesium in women with pregnancyinduced hypertension and preeclampsia in Oredo local Government, Benin Metropolis: A pilot study. African Journal of Medical and Health Sciences, 2013 Jan;12:1-5.
  9. Faisal AR, Ali R, Maha MB, Tariq HK. Sodium imbalance in preeclampsia. Iraqi J Med Sci 2009; 2009 Jan;1:41-48.
  10. Dhokikar GD, Birla VH, Ingale PW, Bende SP, Kadam PS. Study of serum electrolytes in preeclampsia. International Journal of Anatomy Physiology and Biochemistry. 2015 Jan; 2(1):16-20.
  11. Indumati V, Kodliwadmath MV, Sheela MK. Role of serum electrolytes in pregnancy induced hypertension. JCDR. 2011 Feb;5,66-69.
  12. Tabassum H, Al-Jameil N, Ali MN, Khan FA, Al-Rashed M. Status of serum electrolytes in preeclamptic pregnant women of Riyadh, Saudi Arabia. Biomedical Research 2015 Jan;26(2):219-224.
  13. Caughey AB, Stotland NE, Washington AE, Escobar GJ. Maternal ethnicity, paternal ethnicity, and parental ethnic discordance: Predictors of preeclampsia. Obstetrics & Gynecology, 2005 Jul;106:156-161.
  14. Darkwa EO, Djagbletey R, Antwi-Boasiako C, Aryee G, Sottie D, Akowuah A. Serum sodium and potassium levels inpreeclampsia: A case-control study in a large tertiary hospital in Ghana Owusu Darkwa et al., Cogent Medicine, 2017 Sep;4: 1-10
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.