Indian journal of Medical Biochemistry

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VOLUME 23 , ISSUE 2 ( May-August, 2019 ) > List of Articles

Original Article

Effect of Hemodialysis on Trace Elements in Renal Failure Patients

Anusha P Dsouza, Ramlingareddy, Anurag Yadav, Malathi Mala

Keywords : Chronic renal failure, Hemodialysis, Iron, Zinc

Citation Information : Dsouza AP, R, Yadav A, Mala M. Effect of Hemodialysis on Trace Elements in Renal Failure Patients. Indian J Med Biochem 2019; 23 (2):233-235.

DOI: 10.5005/jp-journals-10054-0093

License: CC BY-NC 4.0

Published Online: 01-08-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Hemodialysis patients are at prone for essential trace element deficiency and accumulation of excess harmful trace elements, together of which can affect health burden. During dialysis required renal functions, such as the removal of metabolic waste products, water, correction of the acid-base status and electrolytes are substituted by the artificial purification system. Prone for both accumulation and deficiency of trace elements depends on removal by dialysis, dietary intake, the content of the source water used for dialysis and residual kidney function. This study aimed to evaluate the possible changes in serum iron (Fe) and zinc (Zn) levels in CRF patients undergoing dialysis, pre, and post. It is a case-control hospital-based study (n = 90), Patients included in the present study were all admitted to the Nephrology unit or attending the outpatient department of Nephrology and Dialysis ward. Group IA- Pre-hemodialysis, Group IB- Post-haemodialysis, Group II- Normal healthy controls. Results showed serum zinc levels in both groups of CRF patients (IA, IB) were significantly higher when compared to controls. There was a significantly higher serum level of iron in Group-IB when compared to Group-1A patients. To conclude, the present study has observed significant changes in zinc and iron in CRF patients, pre- and post-hemodialysis.


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