Introduction: Body mass index (BMI) is an important tool for monitoring development in the growing age group. Thyroid hormone affects body weight through changes in basal metabolic rate (BMR). The increasing prevalence of deranged BMI in young girls’ necessities to rule out thyroid dysfunction. Aim: The study objective was to analyze the association between BMI and thyroid function in adolescent girls. Materials and methods: Seventy-five girls of 12–18 years of age group were included in this study. All participants had undergone anthropometric measurements and serum analysis for thyroid-stimulating hormone (TSH) and T4. Based on the growth and BMI chart of the Indian Association of Pediatrics (IAP), the participants were categorized into two groups. Participants with BMI within 25–75 percentiles were categorized as group I and those below 25 and above 75 percentile were categorized as group II. Results: The median values of age, weight, and TSH levels were significantly higher in group II participants when compared with group I. In group II, serum TSH and BMI depicted a highly significant positive correlation (p value = 0.001) while in group I this correlation was 0.044. Conclusion: Serum TSH was found elevated in participants with BMI derangement. The stronger correlation between TSH and BMI suggested regarding the inter-relationship between thyroid hormone and BMI and impact of each other\'s metabolism. Clinical significance: The subclinical serum TSH levels and its correlation with BMI require more detailed study to devise a causal relationship. Thyroid hormones have a role in the development and any derangement in the adolescents affects the development.
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