Indian journal of Medical Biochemistry

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VOLUME 24 , ISSUE 2 ( May-August, 2020 ) > List of Articles

REVIEW ARTICLE

COVID-19: Symphony or Cacophony of Immunology

Parikshit Sen, Neelam Makwana, Binita Goswami

Keywords : Adaptive immunity, Acute respiratory distress syndrome, Cytokine storm, Innate immunity, Pandemic

Citation Information : Sen P, Makwana N, Goswami B. COVID-19: Symphony or Cacophony of Immunology. Indian J Med Biochem 2020; 24 (2):66-75.

DOI: 10.5005/jp-journals-10054-0156

License: CC BY-NC 4.0

Published Online: 05-01-2021

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Coronavirus disease 2019 abbreviated as COVID-19 has emerged out to be the greatest public health problem in the world. Coronavirus disease 2019 is caused by a novel virus belonging to the coronavirus family, which causes respiratory disease. Coronavirus disease 2019 is a highly contagious disease with person-to-person transmission, and now affecting the whole world through community transmission. The disease has spread throughout the world with varied mortality rates in different countries. The disease has higher mortality rates among people with extremes of age and the presence of comorbidities. The present review attempts to provide a snapshot of the various immunological responses against this disease sometimes with disastrous consequences such as the cytokine storm.


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