Indian Journal of Medical Biochemistry

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VOLUME 28 , ISSUE 2 ( May-August, 2024 ) > List of Articles

ORIGINAL RESEARCH ARTICLE

A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure

Suresh Shiva Kumar, Rangaswamy Ranga Raju, Mallikarjun Aradhya, Riyaz A Kalaburgi, Pavithra Venkateshaiah, Sathisha T Gururaja

Keywords : Acute heart failure, Duration of stay, In-patients, N-terminal pro-B-type natriuretic peptide, Prospective observational study

Citation Information : Kumar SS, Raju RR, Aradhya M, Kalaburgi RA, Venkateshaiah P, Gururaja ST. A Correlation Study on Serum Biomarker and Biochemical Parameters in Acute Heart Failure with Duration of Hospital Stay among Patients with Acute Heart Failure. Indian J Med Biochem 2024; 28 (2):41-44.

DOI: 10.5005/jp-journals-10054-0232

License: CC BY-NC 4.0

Published Online: 18-05-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Aims and background: Cardiac biomarker like serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) has revolutionized the diagnosis of heart failure and also plays an important role in prognosticating heart failure. Limited data exist in correlating the level of cardiac biomarkers and biochemical parameters with duration of hospital stay in patients with clinical evidence of acute heart failure. Materials and methods: Our study comprised of 200 inpatients diagnosed with acute heart failure both men and women using convenience sampling method. It is a prospective observational study. The inpatients were from the Department of Cardiology of Shridevi Institute of Medical Sciences and Research Hospital, Tumkur, Karnataka, India. The duration of study was from April 2022 to Sep 2023. Results: There was a positive correlation observed in serum NT-proBNP and potassium values with the duration of stay in the inpatients with acute heart failure (p < 0.05). Serum NT-proBNP was highly significant over a week stay at hospital with a median value of 4784 pg/mL (p < 0.05). Conclusion: The current study highlights the role of serum NT-proBNP and potassium ion as biomarker as well as prognostic factor in the morbidity of acute heart failure in patients. Clinical significance: The estimation of their serum levels may help in early prediction of duration of stay in hospital.


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