Indian Journal of Medical Biochemistry

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VOLUME 21 , ISSUE 2 ( July-December, 2017 ) > List of Articles

RESEARCH ARTICLE

Comparative Study of Serum Calcium in Preeclampsia and Normal Pregnancy at Government Medical College and Hospital, Aurangabad City, India

Citation Information : Comparative Study of Serum Calcium in Preeclampsia and Normal Pregnancy at Government Medical College and Hospital, Aurangabad City, India. Indian J Med Biochem 2017; 21 (2):147-150.

DOI: 10.5005/jp-journals-10054-0039

License: CC BY 3.0

Published Online: 01-12-2013

Copyright Statement:  Copyright © 2017; The Author(s).


Abstract

Introduction

Preeclampsia, a pregnancy-specific disorder, is a global health problem. The major mineral calcium has been proposed to play an important role in the pathogenesis of pre-eclampsia. The present study was aimed to compare the level of serum calcium in normal pregnant women and in preeclampsia and determine the association of serum calcium with severity of the disease.

Study design

This study included 60 pregnant women diagnosed with preeclampsia as cases and 60 healthy pregnant women as controls in the third trimester of gestation. The concentration of total serum calcium was measured in both groups.

Results

Serum calcium level was significantly decreased in preeclamptic women than in normal pregnant women. Serum calcium showed significant negative correlation with systolic and diastolic blood pressure.

Conclusion

Hypocalcemia found in preeclamptic women in our study suggests that serum calcium may have a role in the etiopathogenesis of this disorder. Routine estimation of serum calcium may be useful as a diagnostic marker in preeclampsia.

How to cite this article

Aghade SM, Bavikar JS. Comparative Study of Serum Calcium in Preeclampsia and Normal Pregnancy at Government Medical College and Hospital, Aurangabad City, India. Indian J Med Biochem 2017;21(2):147-150.


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